致死性脑型红斑狼疮中的凝血异常

Paterson A, Timperley W, Slater D

J R Soc Med. 1981 Jan;74(1):53-5. doi: 10.1177/014107688107400110.

Two cases of fatal systemic lupus erythematosus (SLE) with cerebral involvement are described. Both showed widespread microinfarction of the brain secondary to platelet and fibrin thrombi. There was no evidence of vasculitis. Anticoagulants and antiplatelet drugs may have an important role in the management of cerebral SLE.

本文描述了两例伴有脑部受累的致死性系统性红斑狼疮（SLE）病例。两者均显示继发于血小板和纤维蛋白血栓的广泛脑微梗死。未发现血管炎证据。抗凝剂和抗血小板药物可能在脑部SLE的治疗中发挥重要作用。