Adebonojo S A, Adebo O A, Osinowo O, Grillo I A
J Natl Med Assoc. 1981 Jan;73(1):39-42.
Between 1969 and 1979, 20 patients under-went pneumonectomy for tuberculous destroyed lungs (TDL) at the University College Hospital (UCH), Ibadan, Nigeria. Their ages ranged from 9 to 57 years, with an average age of 24 years. The left lung was involved in 16 patients (80 percent) and the right lung in four patients (20 percent). All patients had received treatment for pulmonary tuberculosis (PTB) for over three years, and all patients had negative cultures of acid-fast bacilli (AFB) at the time of operation. Pulmonary function studies were performed in 15 patients, bronchography in 18, and pulmonary angiography in four. Ninteen patients had elective resection because of mild to moderate hemoptysis without mortality. The only death occurred in a 37-year-old man who had emergency resection because of massive hemoptysis. He died intraoperatively of cardiac arrest. One patient developed bronchopleural fistula (BPF), empyema, and wound infection. The fistula closed spontaneously following prolonged chest drainage and pleural irrigation with antibiotics and antituberculous drugs. As a result of our experience with pulmonary tuberculosis in our environment, the authors now recommend elective resection for patients with TDL in order to prevent massive hemoptysis which may prove fatal.
1969年至1979年间,20例患者在尼日利亚伊巴丹大学学院医院(UCH)因结核毁损肺(TDL)接受了肺切除术。他们的年龄在9岁至57岁之间,平均年龄为24岁。16例患者(80%)左肺受累,4例患者(20%)右肺受累。所有患者均接受了超过三年的肺结核(PTB)治疗,且所有患者在手术时痰涂片抗酸杆菌(AFB)培养均为阴性。15例患者进行了肺功能检查,18例进行了支气管造影,4例进行了肺血管造影。19例患者因轻度至中度咯血接受了择期切除,无死亡病例。唯一的死亡发生在一名37岁男性身上,他因大量咯血接受了急诊切除,术中死于心脏骤停。1例患者发生支气管胸膜瘘(BPF)、脓胸和伤口感染。经长时间胸腔引流以及用抗生素和抗结核药物进行胸腔冲洗后,瘘口自行闭合。鉴于我们在当地对肺结核的治疗经验,作者现建议对TDL患者进行择期切除,以预防可能致命的大量咯血。