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多次住院患者入院毒理学检查情况调查

Survey of admission toxicology panels in patients with multiple hospitalizations.

作者信息

Bailey D N

出版信息

J Anal Toxicol. 1980 Jul-Aug;4(4):204-11. doi: 10.1093/jat/4.4.204.

Abstract

Of 1309 different patients with toxicology panels performed on admission to our university medical center during 1978-79, 65 (5.0%) had more than one hospitalization or emergency-room visit. The average patient with multiple admission panels performed during the year was an alert 32-year-old man who presented to the emergency room a mean of 2.2 times, following an episode of suspected drug abuse. The visits were separated by a mean time interval of 2.5 months. An average 1.7 different drugs per patient were found on the admission toxicology screening (usually ethanol, a barbiturate, an opiate, or a phenothiazine). One third of the drugs per patient were positive again on subsequent hospitalizations of the patient. In more than a third of the instances in which repeated drugs were quantitated, the "repeat level" on the subsequent admission was within +/- 17% of that found on the first admission. Laboratory recognition of patients with repetitive admission toxicology screening may facilitate analysis by permitting specific-drug-oriented searches.

摘要

在1978 - 1979年间,于我校医学中心入院时接受毒理学检测的1309名不同患者中,65名(5.0%)有不止一次住院或急诊就诊经历。该年度接受多次入院检测的患者平均为一名32岁警觉男性,因疑似药物滥用事件平均前往急诊室2.2次。就诊间隔的平均时间为2.5个月。入院毒理学筛查发现每名患者平均有1.7种不同药物(通常为乙醇、巴比妥类药物、阿片类药物或吩噻嗪类药物)。患者后续住院时,每名患者三分之一的药物检测结果再次呈阳性。在超过三分之一对重复药物进行定量的情况下,后续入院时的“重复水平”在首次入院时检测值的±17%范围内。对重复进行入院毒理学筛查的患者进行实验室识别,通过允许进行特定药物导向的搜索,可能有助于分析。

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