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家兔自体气管置换实验(作者译)

[Experiments with autogenous tracheal replacement in rabbits (author's transl)].

作者信息

Strauss P, Gorris A, Lenz W

出版信息

Laryngol Rhinol Otol (Stuttg). 1980 Aug;59(8):458-66.

PMID:7464364
Abstract

Stenosis of the cervical trachea could be resected and replaced without tension, if a suitable prosthesis would be available. Postoperative stenosis of the anastomosis would be diminished by lowering the tension. In animal experiments with rabbits we succeeded in producing a tube, which was stabilised by autogenous cartilage and which has a smooth inner surface. This tube was similar to the rabbits trachea with regard to size and mechanical stability. Controlling the regeneration patterns of tracheal epithelium in rabbits there was demonstrated, that rather normal epithelium grew over scarred anastomosis by increased regeneration. The composition of an autogenous tracheal replacement tube could be the first step in reconstruction of parts of the cervical trachea.

摘要

如果能获得合适的假体,颈段气管狭窄可以无张力地切除并置换。通过降低吻合口的张力,可减少术后吻合口狭窄。在对兔子进行的动物实验中,我们成功制作出一种由自体软骨加固且内表面光滑的管子。该管子在尺寸和机械稳定性方面与兔子的气管相似。通过对兔子气管上皮再生模式的研究表明,通过增强再生,相当正常的上皮可在瘢痕化的吻合口上生长。自体气管置换管的制作可能是颈段气管部分重建的第一步。

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