Hopf U, Ramadori G
Leber Magen Darm. 1980 Oct;10(5):277-83.
The reticuloendothelial system of the liver includes endothelial cells, Kupffer cells, fat storing cells and pit cells. Kupffer cells have special surface structures, the so-called fuzzy coat and immunological receptors, which are responsible for phagocytotic activity. The physiological role of the hepatic reticuloendothelial system is clearing various substrates as for instance proteins and lipoproteins, hemoglobin, bilirubin, immune complexes, bacterial toxins, and certain circulating cells. The activity of the reticuloendothelial system can be influenced by blood flow velocity, by opsonins produced by the body itself, and by certain exogenous factors. The function of the reticuloendothelial system may be estimated by methods, which are dependent essentially upon hepatic clearance of intravenously applied, special substances.
肝脏的网状内皮系统包括内皮细胞、库普弗细胞、贮脂细胞和肝自然杀伤细胞。库普弗细胞具有特殊的表面结构，即所谓的绒毛状外衣和免疫受体，它们负责吞噬活性。肝脏网状内皮系统的生理作用是清除各种物质，例如蛋白质和脂蛋白、血红蛋白、胆红素、免疫复合物、细菌毒素以及某些循环细胞。网状内皮系统的活性可受到血流速度、机体自身产生的调理素以及某些外源性因素的影响。网状内皮系统的功能可以通过一些方法来评估，这些方法主要依赖于静脉注射特殊物质后的肝脏清除率。
