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318例脑出血。病理研究(作者译)

[318 cases of intracerebral hemorrhage. A pathologic study (author's transl)].

作者信息

Boudouresques G, Hauw J J, Escourolle R

出版信息

Rev Neurol (Paris). 1980;135(12):845-65.

PMID:7466113
Abstract

The systemic analysis of cerebral hemorrhages (large single and multiple hematomas and small slit-hemorrhages) has been practiced in 318 patients. The emphasis is put on the site of the bleeding and the etiological data. Single hematomas were situated: 1) in 127 cases in the basal ganglia region (26 were medial, 44 intermediate, 48 lateral, 8 quadrilateral and one subthalamic), 2) in 67 cases in cerebral lobes (24: front; 22: temporal; 21 parietal) and 3) in 33 cases in the posterior fossa (19: cerebellum; 14: brain stem). Large hematomas in 71 cases and slit-hemorrhages in 20 others were multiple. In more than one case out of three, lateral hematomas extended into the temporal lobe and in one case out of two, the internal capsule was affected. The incidence of high blood pressure is significantly higher in patients with intermediate haematomas and slit hemorrhages. This factor is often found in lateral or cerebellar hematomas. Anticoagulant therapy is more frequent in lobar hematomas. In 43 cases without any proved etiology, the patients' mean age of death is inferior to that of the whole studied population. These findings are discussed in relation with the literature data.

摘要

对318例脑出血患者(包括单个大血肿、多个血肿及小的裂隙状出血)进行了系统分析。重点关注出血部位和病因学数据。单个血肿的位置分布如下:1)127例位于基底节区(其中26例位于内侧,44例位于中间,48例位于外侧,8例位于四边形区,1例位于丘脑底核);2)67例位于脑叶(24例位于额叶,22例位于颞叶,21例位于顶叶);3)33例位于后颅窝(19例位于小脑,14例位于脑干)。71例为大血肿,另有20例裂隙状出血为多发性。超过三分之一的外侧血肿延伸至颞叶,二分之一的病例内囊受累。中间型血肿和裂隙状出血患者的高血压发病率显著更高。该因素在外侧或小脑血肿中也经常出现。叶性血肿患者接受抗凝治疗的情况更为常见。在43例病因未明的病例中,患者的平均死亡年龄低于整个研究人群。结合文献数据对这些发现进行了讨论。

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