Antonov S, Lalov Kh
Vet Med Nauki. 1978;15(6):42-6.
Studied was the content of total protein and the protein fraction ratio in the blood serum of 14 normal and 58 leukosis-affected cattle. It was found that in the initial phase of leukosis there were no essential changes in the serum proteins. In animals with a more advanced course of the disease (up to 25000 leukocytes per ml, with 65-85 per cent lymphocytes) no drop of the albumins and rise of the alpha-globulins and gamma-globulins were observed, however, there were cases presenting comparatively high lymphocytosis (up to 23000 lymphocytes) without changes in the serum proteins. In animals with well manifested tumoral changes there were almost invariably a strong drop of the albumins (up to 15-20 per cent) and a rise of the alpha1-globulins (up to 15 per cent), alpha2-globulins (up to 18 per cent), and gamma-globulins (up to 51 per cent).
对14头正常牛和58头患白血病牛的血清中的总蛋白含量及蛋白组分比例进行了研究。结果发现，在白血病初期，血清蛋白无明显变化。在病情发展较严重的动物（每毫升白细胞达25000个，淋巴细胞占65% - 85%）中，未观察到白蛋白下降及α球蛋白和γ球蛋白升高的情况，不过，也有淋巴细胞增多较明显（达23000个淋巴细胞）但血清蛋白无变化的病例。在肿瘤变化明显的动物中，几乎总是出现白蛋白大幅下降（达15% - 20%）以及α1球蛋白（达15%）、α2球蛋白（达18%）和γ球蛋白（达51%）升高的情况。
