Boumghar M
Schweiz Med Wochenschr. 1980 Oct 25;110(43):1575-83.
The group of thymic lymphogranulosarcomas are losing their pathologic individuality as autonomous thymic tumors with particular histological and special evolutive characters. Experience shows that a good number of alleged "pseudo-hodgkinian thymomas" have evoluted in the hodgkinian mode. From a total of 56 apparently autonomous thymic tumors operated on in the Department of Surgery A at this hospital, 9 thymic lymphogranulosarcomas have been identified. Our observations confirm that "pseudo-hodgkinian" tumors of the thymic lodge are rather Hodgkin's disease or a primitive-ganglion Hodgkin's disease localized in the thymic lodge. In practice, the discovery of granulomatous tissue in a thymic lodge tumor, even in the absence of typical Sternberg cells, requires a search for other localizations to determine the evolutive stage of the disease. Experience shows that partial or total surgical excision, followed by combined chemotherapy, exploratory laparotomy and radiotherapy, offer the best chances of long term survival at present.
胸腺淋巴颗粒肉瘤组正失去其作为具有特定组织学和特殊演变特征的自主性胸腺肿瘤的病理独特性。经验表明，许多所谓的“假霍奇金氏胸腺瘤”已呈霍奇金氏病的演变方式。在本院外科A部接受手术的56例明显自主性胸腺肿瘤中，已确认9例胸腺淋巴颗粒肉瘤。我们的观察结果证实，胸腺部位的“假霍奇金氏”肿瘤相当于是霍奇金氏病或局限于胸腺部位的原发型神经节霍奇金氏病。实际上，即使在胸腺部位肿瘤中未发现典型的施特恩贝格细胞，发现肉芽肿组织也需要寻找其他部位以确定疾病的演变阶段。经验表明，目前部分或全部手术切除，随后进行联合化疗、剖腹探查术和放疗，提供了最佳的长期生存机会。
