5-氟尿嘧啶的心脏毒性

Tumori. 1980 Oct 31;66(5):635-6. doi: 10.1177/030089168006600511.

A case is reported of cardiotoxicity during a multiple drug treatment with fluorouracil, vincristine and CCNU in a patient with a large bowel cancer without any precedent history of heart disease. The patient had chest pain, with an altered ECG and increased serum levels of alpha HBDH.

报告了一例患有大肠癌且无任何心脏病史的患者，在接受氟尿嘧啶、长春新碱和洛莫司汀联合药物治疗期间发生心脏毒性的病例。该患者出现胸痛，伴有心电图改变和血清α-羟丁酸脱氢酶水平升高。