Maiat V S, Nesterenko Iu A, Buromskaia G A, Atanov Iu P
Vestn Khir Im I I Grek. 1980 Oct;125(10):13-8.
The experience in the treatment of 1800 patients with acute pancreatitis is described. Destructive forms were found in 36% of cases during the last five years. The main methods of treatment and the mortality rate following the methods used are analyzed. The authors believe cytostaticotherapy with the infusion of 5-phthoruracil into the celiac artery and forced diuresis with the infusion of fluids into the celiac artery to be the most perspective methods. The use of the above methods decreased the lethality in destructive forms to 8,3%. The intraaretrial infusion of 5-phthoruracil with antibiotics allowed coping processes of the pancreatic tissue autolysis and avoiding broad sequestration and severe suppurative complications of pancreatitis.
本文描述了对1800例急性胰腺炎患者的治疗经验。在过去五年中，36%的病例出现了坏死性胰腺炎。分析了主要的治疗方法以及采用这些方法后的死亡率。作者认为，经腹腔动脉注入5-氟尿嘧啶的细胞抑制疗法和经腹腔动脉补液的强制利尿疗法是最有前景的方法。使用上述方法可将坏死性胰腺炎的死亡率降至8.3%。经动脉注入5-氟尿嘧啶并联合使用抗生素，有助于控制胰腺组织自溶过程，避免胰腺炎广泛的坏死组织分离和严重的化脓性并发症。
