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[不同年龄红细胞膜蛋白的电泳研究]

[Electrophoretic study of the membrane proteins of erythrocytes of different ages].

作者信息

Grigor'ev G P

出版信息

Vopr Med Khim. 1981 Jan-Feb;27(1):91-6.

PMID:7467210
Abstract

Alterations in membrane proteins of erythrocytes were studied by means of polyacrylamide gel electrophoresis in presence of sodium dodecylsulphate during maturation of the blood cells in an organism, in long-term storage of blood and under conditions of incubation of the erythrocyte shadows in autoplasm. Under the conditions studied the main membrane polypeptides of erythrocytes were shown to be stable. At the same time, maturation of erythrocytes was accompanied by quantitative alterations in some peripheric polypeptides due to interconnected reactions loss of some membrane proteins and their absorption from blood plasma.

摘要

在生物体血细胞成熟过程中、血液长期储存以及红细胞影在自身血浆中孵育的条件下,通过十二烷基硫酸钠存在下的聚丙烯酰胺凝胶电泳研究红细胞膜蛋白的变化。在所研究的条件下,红细胞的主要膜多肽显示是稳定的。同时,红细胞成熟伴随着一些外周多肽的定量变化,这是由于一些膜蛋白的相互关联反应丧失以及它们从血浆中的吸收所致。

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