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羊水表面张力与新生儿呼吸系统顺应性的比较(作者译)

[Comparison of the surface tension of the amniotic fluid with the compliance of the respiratory system of the newborn (author's transl)].

作者信息

Salzer H, Husslein P, Nezbeda J, Simbruner G, Havelec L

出版信息

Wien Med Wochenschr. 1980 Sep 30;130(18):602-5.

PMID:7467375
Abstract

In 51 deliveries between the 27th and 41st week of gestation amniotic fluid was collected ante partum and surface tension measured with the Wilhelmy-balance. The values obtained was compared with the respiratory compliance of the newborns determined immediately post partum. A highly significant correlation (r = -0.83, p less than 0.001) was ascertained. This finding permits a precise prediction of the pulmonary function of the newborn, especially of the especially of the severity degree of a respiratory distress syndrome already by means of amniotic fluid analysis. The less significant correlation between surfactant activity in the amniotic fluid and gestational age (r = -0,48, p less than 0.01) permits the conclusion that pulmonary maturation represents a dynamic process depending upon a variety of known and unknown factors besides the duration of gestation. On the basis of the results of this study the intrauterine and extrauterine fetal risks associated with placental insufficiency can now be estimated more accurately.

摘要

在妊娠27至41周期间的51例分娩中,产前采集羊水并用威尔海姆天平测量表面张力。将获得的值与产后立即测定的新生儿呼吸顺应性进行比较。确定了高度显著的相关性(r = -0.83,p小于0.001)。这一发现允许通过羊水分析精确预测新生儿的肺功能,尤其是呼吸窘迫综合征的严重程度。羊水表面活性物质活性与胎龄之间的相关性较弱(r = -0.48,p小于0.01),这使得可以得出结论,肺成熟是一个动态过程,除了妊娠持续时间外,还取决于多种已知和未知因素。根据本研究结果,现在可以更准确地估计与胎盘功能不全相关的宫内和宫外胎儿风险。

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