Ratzenhofer M, Ertl M
Wien Med Wochenschr. 1980 Nov 15;130(21):683-7.
A diffuse neoplastic peptide-microcarcinoidosis, concentrated in the oral half of the stomach, with 3 small invasive mucosal carcinoids without metastases, was found in a 55 years old woman with a healed duodenal ulcer, cholelithiasis, and obsolete chronic cholecystitis and gastritis. The findings are to be considered within limits as malignant. The only sure hormonal consequence of the microcarcinoidosis was hyperthrophy of the muscularis propria et mucosae (perhaps a Motilin effect?), which was also seen in a previous case. In the clinical picture the symptoms of a chronic gastritis were obscured by gall-stone attacks. The case is of clinical interest as it shows that a diffuse microcarcinoidosis can occur together with one or serveral small gastric carcinoids which have been detected by biobsy and histology. For clarification new biopsies have to be performed.
在一名患有已愈合十二指肠溃疡、胆结石及陈旧性慢性胆囊炎和胃炎的55岁女性患者中,发现了一种弥漫性肿瘤性肽微类癌病,集中于胃的口腔半侧,伴有3个无转移的小侵袭性黏膜类癌。这些发现应在一定程度上被视为恶性。微类癌病唯一确定的激素后果是固有肌层和黏膜层肥厚(可能是胃动素的作用?),这在之前的一个病例中也有观察到。在临床表现中,慢性胃炎的症状被胆结石发作所掩盖。该病例具有临床意义,因为它表明弥漫性微类癌病可与通过活检和组织学检测到的一个或多个小胃类癌同时出现。为了明确诊断,必须进行新的活检。