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用一种新型抗生素复方制剂治疗急性盆腔炎性疾病(作者译)

[Treatment of acute pelvic inflammatory diseases with a new antibiotic compound preparation (author's transl)].

作者信息

Burmucic R

出版信息

Wien Med Wochenschr. 1980 Nov 30;130(22):744-9.

PMID:7467388
Abstract

48 patients with acute pelvic inflammatory diseases (35 cases of acute adnexitis and 13 cases of inflammatory adnexal tumours) were treated with an antibiotic combination of Ampicillin/Oxacillin and Sisomicin. As initial parenteral therapy Ampicillin/Oxacillin 3.0 g was given intravenously twice daily and additionally Sisomicin 75 or 100 mg according to the body-weight was administered intramuscular twice daily. If required a further oral treatment with 500 mg Ampicillin/Dicloxacillin capsules four times a day was carried out. The average duration of parenteral treatment was 6.3 days; together with the oral treatment the duration of antibiotic treatment was 18.5 days. In 43 patients (89.6%) the disease could be cured completely or a distinct improvement could be achieved. Only in 5 cases (10.4%) the results were unsatisfactory. As side-effects allergic reactions were observed in three cases and gastro-enteritis in one case.

摘要

48例急性盆腔炎患者(35例急性附件炎和13例炎性附件肿瘤)接受了氨苄西林/苯唑西林与西索米星的联合抗生素治疗。作为初始的胃肠外治疗,静脉注射氨苄西林/苯唑西林3.0 g,每日两次,另外根据体重肌内注射西索米星75或100 mg,每日两次。如有需要,进一步口服500 mg氨苄西林/双氯西林胶囊,每日四次。胃肠外治疗的平均持续时间为6.3天;加上口服治疗,抗生素治疗的持续时间为18.5天。43例患者(89.6%)的疾病得以完全治愈或有明显改善。只有5例(10.4%)的治疗结果不理想。作为副作用,观察到3例过敏反应和1例肠胃炎。

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