Wara P, Højsgaard A, Amdrup E
Acta Chir Scand. 1980;146(6):431-4.
Preliminary results of endoscopic electrocoagulation combined with Cimetidine are reported in a prospective series of 60 consecutive patients presenting with active bleeding from gastroduodenal ulcer. Coagulation was considered during the initial diagnostic emergency endoscopy, which revealed an accurate identificaion of the bleeding source in 59 patients. Coagulation was accomplished without local complication in 53 patients. Permanent electrohaemostasis was achieved in 47 patients (78%), including 14 patients with clinical indication for surgical intervention. Coagulation could not be applied or failed in 13 patients, requiring operative haemostasis in 11 patients. Though not replacing emergency operation, endoscopic electrocoagulation combined with Cimetidine could be considered an alternative, particularly in patients of advanced age or in the presence of other severe illness.
本文报告了对60例连续的患有胃十二指肠溃疡活动性出血患者进行前瞻性研究的初步结果，这些患者均接受了内镜电凝联合西咪替丁治疗。在初次诊断性急诊内镜检查时考虑进行电凝治疗，该检查在59例患者中准确识别出了出血源。53例患者在电凝治疗过程中未出现局部并发症。47例患者（78%）实现了永久性止血，其中包括14例有手术干预临床指征的患者。13例患者无法进行电凝治疗或治疗失败，其中11例需要手术止血。虽然内镜电凝联合西咪替丁不能替代急诊手术，但可被视为一种替代方法，特别是对于老年患者或患有其他严重疾病的患者。
