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大动脉d-转位的治疗:球囊房间隔造口术后低氧血症的管理

Treatment of d-transposition of the great arteries: management of hypoxemia after balloon atrial septostomy.

作者信息

Henry C G, Goldring D, Hartmann A F, Weldon C S, Strauss A W

出版信息

Am J Cardiol. 1981 Feb;47(2):299-306. doi: 10.1016/0002-9149(81)90401-x.

DOI:10.1016/0002-9149(81)90401-x
PMID:7468481
Abstract

Between 1975 and 1979, a group of 43 patients with d-transposition of the great arteries were diagnosed and underwent Rashkind balloon atrial septostomy at the time of initial catheterization. Thirty-six (88 percent) survived to the time of intraatrial baffle repair, and 31 (72 percent) are long-term survivors, 2 of them now awaiting repair. Palliative operations were performed in nine patients before definitive surgery; four of these patients are long-term survivors. Prostaglandin E1 infusion improved oxygenation and relieved acidosis in four patients. It is concluded that most patients with d-transposition of the great arteries will survive to elective intraatrial baffle repair between 6 and 12 months without surgical palliation in spite of significant hypoxemia. Prostaglandin E1 infusion may be lifesaving and provide sufficient palliation in patients with persistent hypoxemia and acidosis after balloon atrial septostomy.

摘要

1975年至1979年间,一组43例大动脉d型转位患者在初次导管插入术时被诊断出来并接受了拉什金德球囊房间隔造口术。36例(88%)存活至心房内挡板修复时,31例(72%)为长期存活者,其中2例目前正在等待修复。9例患者在确定性手术前接受了姑息性手术;这些患者中有4例为长期存活者。前列腺素E1输注改善了4例患者的氧合并缓解了酸中毒。得出的结论是,尽管存在严重低氧血症,但大多数大动脉d型转位患者在无需手术姑息治疗的情况下,将存活至6至12个月进行择期心房内挡板修复。前列腺素E1输注可能挽救生命,并为球囊房间隔造口术后持续低氧血症和酸中毒的患者提供足够的姑息治疗。

相似文献

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Treatment of d-transposition of the great arteries: management of hypoxemia after balloon atrial septostomy.大动脉d-转位的治疗:球囊房间隔造口术后低氧血症的管理
Am J Cardiol. 1981 Feb;47(2):299-306. doi: 10.1016/0002-9149(81)90401-x.
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引用本文的文献

1
Prostaglandin E2 after septostomy for simple transposition.单纯性大动脉转位行房间隔造口术后的前列腺素E2
Pediatr Cardiol. 2009 May;30(4):447-51. doi: 10.1007/s00246-008-9357-2. Epub 2008 Dec 16.
2
Fate of infants with transposition of the great arteries in relation to balloon atrial septostomy.大动脉转位婴儿与球囊房间隔造口术相关的转归
Br Heart J. 1984 Apr;51(4):371-6. doi: 10.1136/hrt.51.4.371.
3
Use of prostaglandin E2 in management of transposition of great arteries before balloon atrial septostomy.在球囊房间隔造口术之前使用前列腺素E2治疗大动脉转位。
Br Heart J. 1983 Apr;49(4):341-4. doi: 10.1136/hrt.49.4.341.
4
Prostaglandin E2 administration in infants with ductus-dependent cyanotic congenital heart disease.在依赖动脉导管的青紫型先天性心脏病婴儿中给予前列腺素E2。
Eur J Pediatr. 1987 May;146(3):279-82. doi: 10.1007/BF00716473.
5
The pharmacological treatment of patent ductus arteriosus. A review of the evidence.动脉导管未闭的药物治疗。证据综述。
Drugs. 1989 Aug;38(2):249-66. doi: 10.2165/00003495-198938020-00006.
6
Balloon atrial septostomy via the umbilical vein.经脐静脉球囊房间隔造口术
Br Heart J. 1992 Feb;67(2):204-5; author reply 206. doi: 10.1136/hrt.67.2.204-b.