Constantin B, Lavarenne J, Racle J P, Chausset R
Anesth Analg (Paris). 1980;37(9-10):567-72.
The authors revied cardio-vascular physiologics criteria in order to valid a patient with cerebral death for a non mutilant therapeutic study conform to ethical standards as set out in the Declaration of Helsinki. Various tests are discussed. it is necessary to ensure homeostasis and to know if adrenergic receptors are active. The principal problem is the vascular effects of cerebral death on local circulations. It is concluded that it is difficult to use a patient with irreversible coma as a biological model.
作者回顾了心血管生理标准，以便使脑死亡患者能够用于符合《赫尔辛基宣言》所规定伦理标准的非致残性治疗研究。讨论了各种测试。有必要确保体内平衡，并了解肾上腺素能受体是否活跃。主要问题是脑死亡对局部循环的血管影响。得出的结论是，很难将不可逆昏迷患者用作生物学模型。
