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意外动脉内注射酚妥拉明:药物滥用的一种并发症。

Inadvertent intra-arterial injection of phentaramine: a complication of drug abuse.

作者信息

Hamer R, Phelps D

出版信息

Ann Emerg Med. 1981 Mar;10(3):148-50. doi: 10.1016/s0196-0644(81)80381-2.

DOI:10.1016/s0196-0644(81)80381-2
PMID:7469155
Abstract

A female drug abuser inadvertently injected an intravenous injection of an oral anorexiant, phentaramine (Preludin), into her own brachial artery. Severe hand pain, vasospasm, and ischemia occurred. Treatment with regional axillary block, intravenous dextran, intra-arterial priscoline, and salicylate anticoagulation may have influenced a favorable outcome. Intimal damage, vasospasm, and various additive effects after intra-arterial injection contribute to the potential for serious sequelae. Prompt diagnosis, vasodilatation, elevation and compression, pain relief and, in some cases, surgery appear to improve salvage of what is frequently a major extremity injury.

摘要

一名女性药物滥用者意外地将口服食欲抑制剂芬他明(苯丙胺)经静脉注射到自己的肱动脉中。出现了严重的手部疼痛、血管痉挛和局部缺血。采用腋路臂丛神经阻滞、静脉输注右旋糖酐、动脉内注射妥拉苏林以及水杨酸抗凝治疗可能有助于取得良好的治疗效果。动脉内注射后的内膜损伤、血管痉挛及各种累加效应都有可能导致严重的后遗症。及时诊断、血管扩张、抬高并压迫、缓解疼痛,以及在某些情况下进行手术,似乎有助于改善对这种往往是严重肢体损伤的挽救。

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