Boulley A M, Dehan M, Vial M, Hernandorena X, Ropert J C, Laudignon N, Lhermitte C, Gabilan J C
Arch Fr Pediatr. 1980 May;37(5):317-9.
Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia. Blood Indomethacin determination suggested that this disorder was iatrogenic in origin. Clinical, experimental and pharmacological data in the literature support the hypothesis that this condition was due to pulmonary arterial hypertension.
一位在妊娠末期接受过吲哚美辛治疗的母亲所生的双胞胎出现了程度各异但短暂的低氧血症。血液中吲哚美辛的测定表明,这种病症源于医源性因素。文献中的临床、实验和药理学数据支持了这一假说,即这种情况是由肺动脉高压所致。