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猫的遗传性耳聋:盖膜的电子显微镜研究

Hereditary deafness in the cat: an electron-microscopic study of the tectorial membrane.

作者信息

Pedersen E K, Mair I W, Elverland H H

出版信息

Arch Otorhinolaryngol. 1980;229(1):55-68. doi: 10.1007/BF00453752.

DOI:10.1007/BF00453752
PMID:7469938
Abstract

The tectorial membrane is affected at an early stage of the cochlear degeneration in the hereditarily deaf white cat. The membrane first descends towards the organ of Corti with obliteration of the intervening sub-tectorial space in the basal coil during the second post-natal week. Both the microvilli of supporting and Hensen's cells, and the hair cell stereocilia make deep indentations on the under-surface of the membrane. Cells are found insinuated between the tectorial membrane and Corti's organ, and numerous cellular processes occur within the former. A phagocytic function would appear probable for these cells, which seem to originate from the internal sulcus region. The membrane is retracted into the latter around the 2-month stage. At all ages, small spherical structures, which may represent altered interdental cell secretions, are found within the membrane, these becoming calcified in older animals.

摘要

在遗传性耳聋白猫的耳蜗退化早期,盖膜会受到影响。在出生后第二周,盖膜首先向柯蒂氏器下降,基底螺旋中的中间盖膜下间隙消失。支持细胞和亨森细胞的微绒毛以及毛细胞静纤毛在盖膜的下表面形成深深的凹陷。发现有细胞夹在盖膜和柯蒂氏器之间,并且在盖膜内有许多细胞突起。这些细胞似乎起源于内沟区域,可能具有吞噬功能。在2个月左右的阶段,盖膜会回缩到内沟区域。在所有年龄段,在盖膜内都发现有小球形结构,可能代表改变的齿间细胞分泌物,在老年动物中这些结构会钙化。

相似文献

1
Hereditary deafness in the cat: an electron-microscopic study of the tectorial membrane.猫的遗传性耳聋:盖膜的电子显微镜研究
Arch Otorhinolaryngol. 1980;229(1):55-68. doi: 10.1007/BF00453752.
2
Tectorial membrane-organ of Corti relationship during cochlear development.耳蜗发育过程中盖膜与柯蒂氏器的关系。
Anat Embryol (Berl). 1996 Nov;194(5):501-14. doi: 10.1007/BF00185996.
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Attachment of the tectorial membrane revealed by scanning electron microscope.扫描电子显微镜下观察到的盖膜附着情况。
Ann Otol Rhinol Laryngol. 1980 Jul-Aug;89(4 Pt 1):325-30. doi: 10.1177/000348948008900406.
4
Variability of the hereditary deafness in the white cat. II. Histology.白色猫遗传性耳聋的变异性。II. 组织学
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Hereditary deafness in the cat. An electron microscopic study of the stria vascularis and Reissner's membrane.猫的遗传性耳聋。血管纹和Reissner膜的电子显微镜研究。
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Hereditary deafness in the cat. An electron microscopic study of the spiral ganglion.
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Morphological changes of hair cell stereocilia and tectorial membrane in guinea pigs with experimentally induced hydrops.实验性诱导积水豚鼠毛细胞静纤毛和盖膜的形态学变化
Scanning Microsc. 1990 Sep;4(3):705-13; discussion 713-4.
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Stereocilia and tectorial membrane development in the rat cochlea. A SEM study.大鼠耳蜗中静纤毛和盖膜的发育。一项扫描电子显微镜研究。
Anat Embryol (Berl). 1987;175(4):477-87. doi: 10.1007/BF00309683.
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Scanning electron microscopic observations of the under surface of the tectorial membrane.盖膜下表面的扫描电子显微镜观察。
J Electron Microsc (Tokyo). 1979;28(1):36-42.
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Ultrastructural damage in cochleas used for studies of basilar membrane mechanics.用于基底膜力学研究的耳蜗的超微结构损伤。
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本文引用的文献

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Histologic picture of inherited nerve deafness in man and animals.人类和动物遗传性神经性耳聋的组织学图像。
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8
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