关于嗜热菌蛋白酶抑制作用的研究。
Studies on the inhibition of thermolysin.
作者信息
Feder J, Aufderheide N, Wildi B S
出版信息
Experientia Suppl. 1976;26:41-54. doi: 10.1007/978-3-0348-7675-9_3.
PMID:7470
Abstract
Thei nhibition of the thermolysin catalyzed hydrolysis of FA-Gly-Leu-NH2 and FA-Gly-Phe-NH2 has been reported. The results suggest a model for substrate and inhibitor binding involving the hydrophobic specificity pocket, Arg-203 and Glu-143.
摘要
据报道，嗜热菌蛋白酶催化的FA-Gly-Leu-NH2和FA-Gly-Phe-NH2水解反应受到抑制。结果表明了一种涉及疏水特异性口袋、Arg-203和Glu-143的底物和抑制剂结合模型。
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