[Role of mediators in the quantitative and qualitative changes in the intestinal contents of rabbits with experimental cholera intoxication].

Experimental cholera intoxication caused in 40 rabbits (control--40 rabbits) by intravenous injection of cholerogen was accompanied by disturbance of the mediator balance in the blood plasma and the intestinal wall, chiefly in the samll intestine. Against the background of an increased catecholamine content in the intestinal wall the amount of fluid containing mostly the sodium and potassium bicarbonates and chlorides increased in the lumer of its corresponding sections. The detected regularity possibly served as one of the pathogenetic factors in the mechanism of fluid accumulation in the intestine under the effect of cholerogen.