Davis J A, Wadehra V, McIntosh A S, Monaghan J M
Br J Obstet Gynaecol. 1981 Mar;88(3):322-6. doi: 10.1111/j.1471-0528.1981.tb00989.x.
The case is described of a 20 year old pregnant woman with clear cell adenocarcinoma of the vagina who had been exposed to diethyl stilboestrol in utero. This is the second of three cases known to have occurred in Britain. The importance of radical treatment is discussed. Neither cervical nor vaginal intra-epithelial neoplasia were seen histologically, although squamous metaplasia was widespread, and in some areas was immature and showed atypical features which could be misinterpreted as intra-epithelial neoplasia. An area of atypical adenosis was noticed, a hitherto rarely observed feature.
本文描述了一名20岁的阴道透明细胞腺癌孕妇，她在子宫内曾接触己烯雌酚。这是英国已知发生的三例此类病例中的第二例。文中讨论了根治性治疗的重要性。组织学检查未发现宫颈或阴道上皮内瘤变，尽管鳞状化生广泛存在，且在某些区域不成熟并表现出非典型特征，可能会被误诊为上皮内瘤变。还发现了一处非典型腺病，这是一种迄今很少观察到的特征。
