Krause U
Acta Chir Scand. 1978;144(7-8):509-17.
During the eight-year-period from 1968 to 1975 14 patients have been operated on because of ulcerative colitis. A severe, or fulminant, colitis attack was the cause in 48 of these. Most of these patients had been referred from other hospitals. Eight died, six having had a bowel perforation prior to operation, the others having received protracted conservative treatment and came to operation very late. Five of the patients were more than 58 years old. The indications for elective operations were chronic severe symptoms and/or risk of malignant change. In a conservatively treated patient material and with total involvement of their colitis, the cumulative risk of cancer after 30 years follow-up was over 35%. The mortaility in elective surgery was 3%; are all patients up to 1977 included the mortaility is less than 2%. Ileo-rectoanastomoses gave very poor long-term results. Patients with an ileostomy have shown themselves to be well adjusted both socially and psychologically. There are, however, some risk of sexual disturbances.
在1968年至1975年的八年期间,有14名患者因溃疡性结肠炎接受了手术治疗。其中48例是由严重或暴发性结肠炎发作引起的。这些患者大多是从其他医院转诊而来的。8例死亡,6例在手术前发生了肠穿孔,其他患者接受了长期的保守治疗,手术时间很晚。5例患者年龄超过58岁。择期手术的指征是慢性严重症状和/或恶变风险。在一组接受保守治疗且结肠炎完全累及的患者中,经过30年随访,癌症累积风险超过35%。择期手术的死亡率为3%;如果将1977年以前的所有患者都包括在内,死亡率则低于2%。回肠直肠吻合术的长期效果很差。行回肠造口术的患者在社会和心理方面都表现出良好的适应性。然而,存在一些性方面紊乱的风险。