Aldridge J W, Anderson R J, Murphy J T
Can J Physiol Pharmacol. 1980 Oct;58(10):1192-201. doi: 10.1139/y80-182.
Monkeys were prepared for chronic recording of single neurons in the caudate nucleus (Cd) or globus pallidus (GP) during learned wrist flexion-extension movements triggered by visual and somatic sensory inputs. Almost two-thirds of GP cells and more than one-third of Cd cells modified their discharge during these tasks. Three categories of response types were observed. The first was movement related. The second type was event related, in which the cells responded to either the onset or offset of the sensory inputs regardless of the correcting movement direction. A third type combined elements of the first two categories and was termed complex. These cells responded to complex abstractions of the sensory-motor event. A latency analysis indicated that the majority of cells was not involved in initiating movements but may have participated in movement execution. The results of this experiment suggest that during voluntary movement the basal ganglia activity is correlated with motor outputs, sensory inputs, and perceptual abstractions of these sensory-motor events. As such the results are compatible with an influence by diverse regions of cerebral cortex on basal ganglia neurons during the movement control process.
通过视觉和躯体感觉输入触发学习性腕部屈伸运动期间，对猴子进行了尾状核（Cd）或苍白球（GP）单个神经元的慢性记录准备。在这些任务中，近三分之二的GP细胞和超过三分之一的Cd细胞改变了它们的放电。观察到三类反应类型。第一类与运动相关。第二类与事件相关，其中细胞对感觉输入的开始或结束做出反应，而不管纠正运动方向如何。第三类结合了前两类的元素，被称为复杂型。这些细胞对感觉运动事件的复杂抽象做出反应。潜伏期分析表明，大多数细胞不参与启动运动，但可能参与了运动执行。该实验结果表明，在自主运动期间，基底神经节活动与运动输出、感觉输入以及这些感觉运动事件的感知抽象相关。因此，这些结果与运动控制过程中大脑皮层不同区域对基底神经节神经元的影响是一致的。
