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腹腔注射钙对大鼠体温及热应激抵抗力的影响。

Influence of intraperitoneal administration of calcium on body temperature and resistance to thermal stress in rats.

作者信息

Prebendowski J, Lewin-Kowalik J

出版信息

Acta Physiol Pol. 1978 Sep-Oct;29(5):459-64.

PMID:747108
Abstract

Intraperitoneal administration of calcium excess (11.26--21.18 mmol/kg of body weight) in rats at room temperature caused a distinct, significant decrease in body temperature (p less than 0.001). H ypothermic animals obtained in this way demonstrated, however, a significant decrease in resistance to quick heating as compared to controls. It was manifested by lower (by approx. 1.4 degrees C) lethal temperature (p less than 0.001), shorter (by approx. 8 min 12 sec) survival time (p less than 0.02) and higher rate of body temperature increase (by approx. 0.05 degrees C/min, p less than 0.001) in comparison with control rats.

摘要

在室温下给大鼠腹腔注射过量钙(11.26 - 21.18毫摩尔/千克体重)会导致体温明显显著下降(p < 0.001)。然而,通过这种方式获得的低温动物与对照组相比,对快速加热的抵抗力显著降低。这表现为致死温度更低(约低1.4摄氏度,p < 0.001)、存活时间更短(约短8分12秒,p < 0.02)以及体温升高速率更高(约0.05摄氏度/分钟,p < 0.001),与对照大鼠相比。

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