Beller F K, Schnepper E
Dtsch Med Wochenschr. 1981 Mar 13;106(11):329-34. doi: 10.1055/s-2008-1070312.
So-called nipple-preserving operations were performed as primary treatment of mammary carcinoma, predominantly in stage T1, in 135 women. The operation consisted of subcutaneous mastectomy, axillary lymphadenectomy, nipple biopsy and X-ray therapy. Most of the patients in whom more than two lymph nodes had carcinomatous changes also received chemotherapy. Survival of more than five years was achieved in 48 patients in stage T1. One woman died of carcinoma; in six there was further growth with metastases. In no case was there further growth in the nipple region. Although the numbers are small one can already state that the results are no worse than after more radical operations.
对135名女性的乳腺癌主要在T1期进行了所谓的保乳手术作为初始治疗。手术包括皮下乳房切除术、腋窝淋巴结清扫术、乳头活检和X线治疗。大多数有两个以上淋巴结发生癌变的患者也接受了化疗。T1期48名患者存活超过5年。1名女性死于癌症;6名患者出现肿瘤进展并伴有转移。乳头区域均未出现肿瘤进展。尽管数量较少,但可以说结果并不比更根治性手术差。