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[新生儿喉麻痹。病程与治疗。56例(作者译)]

[Neonatal laryngeal paralysis. Course and treatment. 56 cases (author's transl)].

作者信息

Narcy P, Manac'h Y, Sitbon G, Pons G

出版信息

Ann Otolaryngol Chir Cervicofac. 1978 Jul-Aug;95(7-8):461-8.

PMID:747279
Abstract

56 laryngeal paralyses were seen in newborn infants between 1970 and 1976 (25 bilateral, 31 unilateral). The aetiology was obstetric trauma in 11 cases, nuclear agenesis in 7 cases, a severe neurological disorder (spina bifida, hydrocephaly, microcephaly, lesions of the central nervous system) in 13 cases, and congenital heart disease in 3 cases. In 10 cases, the paralysis was present in isolation. The initial state was not recorded in 11 cases. The course varied according to the aetiology: 5 deaths, 4 due to the severity of neurological problems. Regression, which invariably occured before the end of the 6th month, was seen in all the cases with an obstetric aetiology and in 50% of those in which the paralysis was present in isolation. There was persistence in the majority of neurological, nuclear or central causes. However, subsequent tolerance of persistent forms was good in all those patients followed-up on a regular basis, apart from 5 who underwent surgery. Treatment consisted of intubation for forms poorly tolerated initially, for the first few weeks. Tracheotomy did not prove necessary in any case. 5 patients underwent surgery: arytenoidectomy or arytenoidopexy via an extralaryngeal approach.

摘要

1970年至1976年间,在新生儿中发现56例喉麻痹(25例双侧,31例单侧)。病因包括:产科创伤11例,核发育不全7例,严重神经系统疾病(脊柱裂、脑积水、小头畸形、中枢神经系统病变)13例,先天性心脏病3例。10例为孤立性麻痹。11例未记录初始状态。病程因病因而异:5例死亡,4例死于神经系统问题的严重性。所有产科病因的病例以及50%孤立性麻痹的病例在6个月前均出现恢复。大多数神经系统、核或中枢性病因导致的麻痹持续存在。然而,除5例接受手术的患者外,所有定期随访的患者对持续性麻痹的耐受性良好。治疗包括对最初耐受性差的病例在最初几周进行插管。在任何情况下均未证明有必要进行气管切开术。5例患者接受了手术:通过喉外途径进行杓状软骨切除术或杓状软骨固定术。

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