Kanemoto N, Wang Y, Fukushi H, Ibukiyama C, Takeuchi T, Sato T, Takahashi T
Department of Internal Medicine, Tokai University School of Medicine, Kanagawa.
J Cardiol. 1995 Sep;26(3):149-58.
Acute myocardial infarction (AMI) causing ST depression and T wave inversion has been diagnosed as subendocardial or non-Q myocardial infarction. However, some patients eventually develop strictly posterior infarction with a lesion of the left circumflex coronary artery (LCX). This study attempted to determine the electrocardiographic (ECG) characteristics of such myocardial infarction in 32 patients with definite AMI in whom ECG showed no hyperacute T waves or ST elevation and the LCX was an infarct-related coronary artery. ECG on admission (< 6 hours from the onset), at 24 hours, and on the 14th day were analyzed to evaluate QRS, ST, T, and U waves using calipers and magnifying lens. Sixty-six patients with normal circulation served as controls. The characteristic ECG findings on admission were ST depression in chest leads, and prominent positive U waves in leads V2 or V3 with relatively small T waves. Based on these results we proposed new ECG criteria: 1) ST depression > or = 0.1 mV in 2 consecutive chest leads, 2) prominent positive U wave > or = 0.1 mV in leads V2 or V3, 3) T/U ratio in leads V2 or V3 < or = 4. Considering two of the above criteria as positive, the sensitivity was 71.9%, the specificity 97.0%, and the diagnostic accuracy 88.8%. In 85.2% of the patients, ST depression returned to the baseline by 24 hours. As the amplitude of the U waves decrease gradually, the T/U ratio increased. The R/S ratio in leads V1 or V2 became > or = 1 by 24 hours in 46.4% and the amplitude of R wave in lead V1 increased gradually. T waves in the right precordial leads increased with time. These findings were consistent with isolated strictly posterior myocardial infarction. From these results we identified new ECG criteria: 1) R/S ratio in leads V1 or V2 > or = 1, 2) R wave > or = 0.7 mV in lead V1, 3) T wave > or = 0.5 mV in lead V1. Considering any of the above criteria as positive, the sensitivity was 72.0%, the specificity 87.9%, and the diagnostic accuracy 86.7% on the 14th day. These new ECG criteria of strictly posterior myocardial infarction with the LCX as an infarct-related coronary artery apply at less than 6 hours or at 24 hours from the onset of the symptoms.
导致ST段压低和T波倒置的急性心肌梗死(AMI)已被诊断为心内膜下或非Q波心肌梗死。然而,一些患者最终会发展为累及左旋支冠状动脉(LCX)病变的严格意义上的后壁心肌梗死。本研究试图确定32例确诊AMI患者的此类心肌梗死的心电图(ECG)特征,这些患者的ECG未显示超急性期T波或ST段抬高,且LCX为梗死相关冠状动脉。分析入院时(发病后<6小时)、24小时及第14天的ECG,使用卡尺和放大镜评估QRS波、ST段、T波和U波。66例循环系统正常的患者作为对照。入院时特征性的ECG表现为胸导联ST段压低,V2或V3导联U波显著正向且T波相对较小。基于这些结果,我们提出了新的ECG标准:1)连续2个胸导联ST段压低≥0.1 mV;2)V2或V3导联U波显著正向≥0.1 mV;3)V2或V3导联T/U比值≤4。将上述标准中的两条视为阳性,敏感性为71.9%,特异性为97.0%,诊断准确性为88.8%。85.2%的患者在24小时时ST段压低恢复至基线。随着U波振幅逐渐降低,T/U比值升高。46.4%的患者在24小时时V1或V2导联R/S比值≥1,且V1导联R波振幅逐渐增加。右胸前导联T波随时间增高。这些表现与孤立的严格意义上的后壁心肌梗死一致。根据这些结果,我们确定了新的ECG标准:1)V1或V2导联R/S比值≥1;2)V1导联R波≥0.7 mV;3)V1导联T波≥0.5 mV。将上述任何一条标准视为阳性,在第14天时敏感性为72.0%,特异性为87.9%,诊断准确性为86.7%。这些以LCX为梗死相关冠状动脉的严格意义上的后壁心肌梗死的新ECG标准适用于症状发作后不到6小时或24小时。