Morgenstern L B, Pardo C A
Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA.
J Rheumatol. 1995 Aug;22(8):1593-5.
We describe a man treated with cyclophosphamide and prednisone for Wegener's granulomatosis who developed biopsy proven progressive multifocal leukoencephalopathy (PML). Upon discontinuation of immunosuppression he made a dramatic recovery. As immunosuppressant use is increasing we draw attention to this potentially fatal, but reversible neurologic disease.
我们描述了一名接受环磷酰胺和泼尼松治疗韦格纳肉芽肿的男性患者，该患者经活检证实患进行性多灶性白质脑病（PML）。停用免疫抑制治疗后，他病情显著好转。随着免疫抑制剂使用的增加，我们提请注意这种潜在致命但可逆转的神经系统疾病。
