大T抗原介导的同源重组所需的多瘤病毒复制起点元件。
Elements of the polyomavirus replication origin required for homologous recombination mediated by large T antigen.
作者信息
Laurent S, Bastin M
机构信息
Department of Biochemistry, University of Sherbrooke, Quebec, Canada.
出版信息
J Virol. 1995 Nov;69(11):7304-8. doi: 10.1128/JVI.69.11.7304-7308.1995.
Abstract
We introduced various elements of the polyomavirus origin of DNA replication into the genome of rat cells, and we analyzed their capacity to elicit rearrangements within the integrated sequences when exposed to large T antigen. The cis-acting sequences required for homologous recombination were those that make up a functional replication origin.
摘要
我们将多瘤病毒DNA复制起点的各种元件导入大鼠细胞基因组中，并分析了它们在暴露于大T抗原时引发整合序列内重排的能力。同源重组所需的顺式作用序列是那些构成功能性复制起点的序列。
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本文引用的文献
1
High-frequency recombination mediated by polyomavirus large T antigen defective in replication.由复制缺陷的多瘤病毒大T抗原介导的高频重组。
J Virol. 1993 Apr;67(4):1788-95. doi: 10.1128/JVI.67.4.1788-1795.1993.
2
3
Amplification mediated by polyomavirus large T antigen defective in replication.由复制缺陷的多瘤病毒大T抗原介导的扩增。
J Virol. 1993 Aug;67(8):5025-9. doi: 10.1128/JVI.67.8.5025-5029.1993.
4
Transcription activation mediated by chromosomal inversion in rat cells.大鼠细胞中染色体倒位介导的转录激活。
Oncogene. 1994 Mar;9(3):781-9.
5
Intrachromosomal recombination mediated by the polyomavirus large T antigen.
Virology. 1995 Jan 10;206(1):227-33. doi: 10.1016/s0042-6822(95)80037-9.
6
Spontaneous changes in nucleotide sequence in proviruses of spleen necrosis virus, an avian retrovirus.脾脏坏死病毒（一种禽逆转录病毒）原病毒核苷酸序列的自发变化。
Proc Natl Acad Sci U S A. 1982 Feb;79(4):1230-4. doi: 10.1073/pnas.79.4.1230.
7
Amplification and excision of integrated polyoma DNA sequences require a functional origin of replication.整合的多瘤病毒DNA序列的扩增和切除需要一个功能性复制起点。
Cell. 1984 Apr;36(4):943-9. doi: 10.1016/0092-8674(84)90044-8.
8
Non-contiguous segments of the polyoma genome required in cis for DNA replication.多瘤病毒基因组中DNA复制顺式作用所需的非连续片段。
J Mol Biol. 1982 Nov 15;161(4):533-50. doi: 10.1016/0022-2836(82)90406-5.
9
Requirements for excision and amplification of integrated viral DNA molecules in polyoma virus-transformed cells.多瘤病毒转化细胞中整合病毒DNA分子的切除和扩增要求。
J Virol. 1982 Aug;43(2):617-28. doi: 10.1128/JVI.43.2.617-628.1982.
10
Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors.克隆至M13载体的DNA片段的寡核苷酸定向诱变
Methods Enzymol. 1983;100:468-500. doi: 10.1016/0076-6879(83)00074-9.
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