Hashimoto K, Tanaka Y, Asahi N, Ohishi S, Sakio H, Okuda C
Second Department of Anesthesiology, Dokkyo University School of Medicine, Tochigi.
Masui. 1995 Aug;44(8):1139-42.
The incidence of postoperative convulsive seizure was compared retrospectively during either isoflurane or sevoflurane anesthesia in patients after craniotomy. Overall, 5 of a total of 125 patients suffered convulsive seizures after craniotomy: 2 (4%) of 45 patients with isoflurane anesthesia and 3 (4%) of 80 patients with sevoflurane anesthesia. No significant differences were observed between these two groups. The duration of anesthesia and duration of the MAC.h were similar between these two groups. The occurrence of postoperative convulsive seizure was not related with the inhalational anesthetic agents, the underlying disorders and patient characteristics. It is suggested that either isoflurane or sevoflurane anesthesia in neurosurgical patients may have no specific relationship with the postoperative convulsive seizures.
回顾性比较开颅术后患者在异氟烷或七氟烷麻醉期间术后惊厥发作的发生率。总体而言，125例患者中有5例在开颅术后发生惊厥发作：异氟烷麻醉的45例患者中有2例（4%），七氟烷麻醉的80例患者中有3例（4%）。两组之间未观察到显著差异。两组之间的麻醉持续时间和最低肺泡有效浓度小时数相似。术后惊厥发作的发生与吸入麻醉剂、基础疾病和患者特征无关。提示神经外科患者使用异氟烷或七氟烷麻醉可能与术后惊厥发作无特定关系。
