Kondo S, Fuke T, Tokiwa M, Ryuu H, Yano J, Sakai C, Koga M, Hori S, Yoshimizu Y, Hirohata I
Clinical Laboratory, Kurume University Hospital.
Rinsho Byori. 1995 Sep;43(9):953-9.
Forty-two female college students underwent fitness-type exercise over a 13 week period. The students exercised an average of two times a week for 30 minute periods at 50% levels of VO2 . max. Iron status and hematological laboratory data were monitored at three points in time; at the initiation of exercise, at the termination of exercise and 3 months later. Serum ferritin levels in a third of the students were lower than 12ng/ml. Red blood cell counts decreased during exercise, and returned to the pre-exercise levels 3 months later. The number of circulatory reticulocytes and mean corpuscular hemoglobin concentration were increased significantly after the exercise and the effects were still observed 3 months later, independent of the iron status. In the lower ferritin group, erythropoietin levels decreased significantly during the post-exercise period. The average serum ferritin levels while showing no significant changes during exercise, increased significantly during the post-exercise period, in the normal ferritin group. We discussed possible mechanisms, among them iron metabolism, by which physical training may facilitate erythropoiesis. However, no definite conclusions have been reached.
42名女大学生在13周的时间里进行了健身类运动。这些学生平均每周锻炼两次,每次30分钟,运动强度为最大摄氧量(VO2.max)的50%。在三个时间点监测了铁状态和血液学实验室数据,分别是运动开始时、运动结束时和3个月后。三分之一学生的血清铁蛋白水平低于12ng/ml。红细胞计数在运动期间下降,并在3个月后恢复到运动前水平。运动后循环网织红细胞数量和平均红细胞血红蛋白浓度显著增加,且3个月后仍观察到这种影响,与铁状态无关。在铁蛋白水平较低的组中,运动后促红细胞生成素水平显著下降。在正常铁蛋白组中,血清铁蛋白平均水平在运动期间无显著变化,但在运动后显著升高。我们讨论了体育锻炼促进红细胞生成的可能机制,其中包括铁代谢。然而,尚未得出明确结论。