Fontan R, Sansonnens R, Rioche M, Ben Zakour L, Bel Hadj A
Arch Inst Pasteur Tunis. 1978 Mar-Jun;55(1-2):35-50.
The authors report the clinical and epizootic evolution of an epizooty, characterized by pseudo-tumours, observed on some vipers (Vipera lebetina) maintained in captivity at the "institut Pasteur de Tunis". The disease was characterized by 2.3 cm size nodules, scattered under the skin or into splanchnic cavities. These ones, spherical and well capsuled, were formed by a mass of clear rounded cells (histiocytes or monocytes), the necrotic central area of which contained innumerable bacteria. Several reviewed works show that this appearance of chronic abcess is a common and univocal reaction to various pathogenic factors, such as bacteria and parasites. As to etiology, the authors have doubt about the pathological role of the germs which they have identified (Salmonella and other anterobacteria) because these latter belong to the normal microbial flora of snakes and are, in the present case, probably occasional infective agents only.
作者报告了在突尼斯巴斯德研究所圈养的一些黎凡特蝰蛇(Vipera lebetina)身上观察到的一场以假肿瘤为特征的动物流行病的临床和流行演变情况。该病的特征是在皮肤下或内脏腔中散在有大小为2.3厘米的结节。这些结节呈球形,包膜良好,由一团透明的圆形细胞(组织细胞或单核细胞)构成,其坏死的中心区域含有无数细菌。几篇综述性著作表明,这种慢性脓肿的表现是对各种致病因素(如细菌和寄生虫)的常见且明确的反应。至于病因,作者对他们所鉴定出的病菌(沙门氏菌和其他肠道杆菌)的病理作用表示怀疑,因为这些病菌属于蛇的正常微生物群落,在本病例中可能只是偶然的感染因子。