Goko C, Ohokubo T, Hoshino R, Kaneko K
Department of Cardiovascular Surgery, Nakadori General Hospital, Akita, Japan.
Kyobu Geka. 1995 Sep;48(10):877-9.
A 53-year-old woman was admitted suffering from high grade fever. Laboratory findings revealed leukocytosis, high CRP, high erythrocyte sedimentation rate and remarkable elevation of serum alkaline phosphatase level. Echocardiogram demonstrated left atrial tumor which was later diagnosed as myxoma. Although remarkable elevation of serum alkaline phosphatase level often indicates malignant disease, tumor makers were normal level and whole body computerized tomography couldn't detect other noncardiac diseases. Because of patient's deterioration due to sustained high grade fever, the left atrial tumor was excised. After the excision of the left atrial myxoma, patient's clinical signs and symptoms disappeared, and the serum alkaline phosphatase level was gradually normalized. We conclude that the cause of remarkable elevation of serum alkaline phosphatase level was the left atrial myxoma.
一名53岁女性因高热入院。实验室检查结果显示白细胞增多、C反应蛋白升高、红细胞沉降率升高以及血清碱性磷酸酶水平显著升高。超声心动图显示左心房肿瘤,后来被诊断为黏液瘤。尽管血清碱性磷酸酶水平显著升高通常提示恶性疾病,但肿瘤标志物处于正常水平,全身计算机断层扫描未发现其他非心脏疾病。由于患者因持续高热病情恶化,遂切除左心房肿瘤。切除左心房黏液瘤后,患者的临床症状和体征消失,血清碱性磷酸酶水平逐渐恢复正常。我们得出结论,血清碱性磷酸酶水平显著升高的原因是左心房黏液瘤。