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[支气管肺部疾病患者的外呼吸、气体交换及血流动力学的相互关系特点]

[Characteristics of interrelations of external respiration, gas exchange and hemodynamics in patients with bronchopulmonary diseases].

作者信息

Sandrikov V A, Chizhov A I, Ambat'ello N G, Tsybikova E B

出版信息

Khirurgiia (Mosk). 1995(5):54-6.

PMID:7474707
Abstract

In 60 patients with stage II-III bronchogenic carcinoma of the lung the following procedures were included in the complex of preoperative functional examination: spiro-body-plethysmography, catheterization of the right heart, and simultaneous examination of gas exchange using a DELTATRAC MBM-100 metabolic monitor. To evaluate the lung diffusion capacity and the dimensions of the arteriovenous shunt, oxygen mixtures differing in O2 concentration were used. The results were interpreted within the framework of a homogeneous model of lung gas exchange realized on a PC/AT personal computer. The interrelationship of ventilation disorders with hemodynamic and lung gas--exchange function was studied. Arterial hypoxemia was mainly observed in obstructive and mixed disorders of ventilation function and was more marked in the latter. Primary disturbance of the lung diffusion capacity was found to be the leading link in the development of acute respiratory insufficiency after the operation.

摘要

在60例II - III期肺支气管癌患者中,术前功能检查综合项目包括:体容积肺量计检查、右心导管插入术以及使用DELTATRAC MBM - 100代谢监测仪同步检查气体交换。为评估肺弥散能力和动静脉分流大小,使用了氧气浓度不同的氧混合气。结果在基于PC/AT个人计算机实现的肺气体交换均匀模型框架内进行解读。研究了通气障碍与血流动力学及肺气体交换功能之间的相互关系。动脉血氧不足主要见于通气功能的阻塞性和混合性障碍,且在后者中更为明显。肺弥散能力的原发性障碍被认为是术后急性呼吸功能不全发生过程中的主要环节。

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