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[乙型血友病与主动脉冠状动脉搭桥术]

[Hemophilia B and aortocoronary bypass].

作者信息

Dimitrova A, Tsarianski G, Aleksandrov V, Kereshka P, Nachev G, Chirkov A

出版信息

Khirurgiia (Sofiia). 1995;48(1):76-9.

PMID:7474765
Abstract

We describe a case of a patient with moderate hemophilia B, undergoing CABG. Substitution therapy was realized with factor IX concentrate (Bebulin-TIM4-IMMUNO). We discuss which of the following factors: hypothermia, hemodilution of heparinisation has a substantial role in alteration of FIX coagulant activity during cardiopulmonary bypass.

摘要

我们描述了一例中度B型血友病患者接受冠状动脉搭桥术（CABG）的病例。使用凝血因子IX浓缩物（Bebulin-TIM4-IMMUNO）进行替代治疗。我们讨论了以下哪些因素：低温、血液稀释或肝素化在体外循环期间对FIX凝血活性的改变中起重要作用。

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引用本文的文献

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Myocardial infarction, other arterial thrombosis and invasive coronary procedures, in hemaophilia B: a critical evaluation of reported cases.乙型血友病患者的心肌梗死、其他动脉血栓形成及侵入性冠状动脉手术：对报告病例的批判性评估
J Thromb Thrombolysis. 2005 Aug;20(1):43-6. doi: 10.1007/s11239-005-2227-3.