Dimitrova A, Tsarianski G, Aleksandrov V, Kereshka P, Nachev G, Chirkov A
Khirurgiia (Sofiia). 1995;48(1):76-9.
We describe a case of a patient with moderate hemophilia B, undergoing CABG. Substitution therapy was realized with factor IX concentrate (Bebulin-TIM4-IMMUNO). We discuss which of the following factors: hypothermia, hemodilution of heparinisation has a substantial role in alteration of FIX coagulant activity during cardiopulmonary bypass.
我们描述了一例中度B型血友病患者接受冠状动脉搭桥术(CABG)的病例。使用凝血因子IX浓缩物(Bebulin-TIM4-IMMUNO)进行替代治疗。我们讨论了以下哪些因素:低温、血液稀释或肝素化在体外循环期间对FIX凝血活性的改变中起重要作用。