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[红细胞单采术对真性红细胞增多症患者左心状态的影响:超声心动图检查结果]

[Effects of erythrocytopheresis on the state of the left heart in patients with polycythemia vera: echocardiographic findings].

作者信息

Bessmel'tsev S S, Zamotina T B

出版信息

Klin Med (Mosk). 1995;73(4):80-2.

PMID:7474832
Abstract

Functional response of the left ventricle (LV) and left atrium to erythrocytapheresis (EA) was studied in 20 patients. At admission, the patients had enlarged LV and low myocardial contractility. By cardiac and stroke volume indices two types of central hemodynamics were identified (hyperkinetic and hypokinetic) dependent on PV duration and concomitant cardiac pathology. These correlations were inferred basing on comparisons of echo-CG findings to data on the patients' age, sex, PV history, associated heart disease, packed cell volume. EA produced positive changes in echo-CG indices with complete normalization of cardiac output in some cases. This is supposed to be due to EA ability to limit foci of myocardial damage and to mobilize cardiac reserves.

摘要

对20例患者研究了左心室(LV)和左心房对红细胞单采术(EA)的功能反应。入院时,患者左心室增大且心肌收缩力降低。根据每搏量和心输出量指数,根据血浆置换(PV)持续时间和伴随的心脏病理情况确定了两种类型的中心血流动力学(高动力型和低动力型)。这些相关性是基于超声心动图(echo-CG)检查结果与患者年龄、性别、PV病史、相关心脏病、红细胞压积数据的比较推断出来的。EA使echo-CG指标产生了积极变化,在某些情况下心输出量完全恢复正常。这被认为是由于EA能够限制心肌损伤灶并调动心脏储备。

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