Schandler S L, Cohen M J, Vulpe M, Frank S E
Addiction Research Laboratory, Department of Veterans Affairs Medical Center, Long Beach, California 90822, USA.
J Stud Alcohol. 1995 Sep;56(5):522-7. doi: 10.15288/jsa.1995.56.522.
Of the many factors that affect the occurrence of and rehabilitation from spinal cord injury, alcohol use and abuse are particularly prominent. Persons with a family history of alcoholism are at greater risk for alcohol abuse and alcoholism. Preliminary data show a much higher than normal proportion of these persons in the spinal cord injured population. If these data are reliable, they may show that family history of alcoholism is a premorbid or comorbid factor to the occurrence of accidents that results in catastrophic injuries. Our investigation represented an evaluation of this premise.
Male volunteer subjects (N = 100) were selected from inpatient and outpatient populations of a Veterans Affairs spinal cord injury service. Subjects received a comprehensive interview and completed two standardized questionnaires and a general information form designed to evaluate their past and present use of alcohol and the use of alcohol by their parents and relatives.
The incidence (45%) of spinal cord injured patients with a family history of alcoholism was over four times that found in the general population. Spinal cord injured subjects with a family history of alcoholism reported significantly more problems with alcohol before, at the time of, and after their injury.
The data suggest a relationship between the predisposition to alcoholism and accidents that result in catastrophic injury.
在影响脊髓损伤发生及康复的诸多因素中，酒精使用与滥用尤为突出。有酗酒家族史的人酗酒和患酒精中毒症的风险更高。初步数据显示，脊髓损伤人群中这类人的比例远高于正常水平。如果这些数据可靠，可能表明酗酒家族史是导致灾难性损伤事故发生的病前或共病因素。我们的调查旨在评估这一假设。
从退伍军人事务部脊髓损伤服务的住院和门诊患者中选取男性志愿者受试者（N = 100）。受试者接受了全面访谈，并完成了两份标准化问卷以及一份旨在评估他们过去和现在的酒精使用情况以及其父母和亲属酒精使用情况的一般信息表。
有酗酒家族史的脊髓损伤患者的发生率（45%）是普通人群的四倍多。有酗酒家族史的脊髓损伤受试者报告称，在受伤前、受伤时和受伤后，他们在酒精方面存在的问题明显更多。
数据表明酗酒易感性与导致灾难性损伤的事故之间存在关联。
