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呼吸状态对大鼠肝线粒体单胺氧化酶活性的影响。

The influence of respiratory state on monoamine oxidase activity in rat liver mitochondria.

作者信息

Smith G S, Reid R A

出版信息

Biochem J. 1978 Dec 15;176(3):1011-14. doi: 10.1042/bj1761011.

DOI:10.1042/bj1761011
PMID:747641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1186328/
Abstract

Changes in the respiratory state of rat liver mitochondria caused significant changes (up to 10-fold) in the rates of oxidative deamination of tyramine, indicating interactions between the inner coupling membrane and the monoamine oxidase sites in the outer membrane, and suggesting the possibility that monoamine oxidase is regulated by the thermodynamic state of the mitochondria.

摘要

大鼠肝线粒体呼吸状态的变化导致酪胺氧化脱氨速率发生显著变化（高达10倍），这表明线粒体内膜耦合膜与外膜中的单胺氧化酶位点之间存在相互作用，并提示单胺氧化酶可能受线粒体热力学状态调控。

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本文引用的文献

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Myokinase and adenosinetriphosphatase in oxidative phosphorylation.氧化磷酸化中的肌激酶和三磷酸腺苷酶
J Biol Chem. 1951 Aug;191(2):485-500.
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ANTIBIOTIC STUDIES. II. INHIBITION OF PHOSPHORYL TRANSFER IN MITOCHONDRIA BY OLIGOMYCIN AND AUROVERTIN.抗生素研究。II. 寡霉素和金褐霉素对线粒体中磷酸转移的抑制作用。
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INHIBITION BY ATRACTYLOSIDE OF THE BINDING OF ADENINE-NUCLEOTIDES TO RAT-LIVER MITOCHONDRIA.苍术苷对腺嘌呤核苷酸与大鼠肝脏线粒体结合的抑制作用。
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Respiratory enzymes in oxidative phosphorylation. III. The steady state.氧化磷酸化中的呼吸酶。III. 稳态
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An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study.与肝线粒体外膜相关的电子传递系统。一项生化与形态学研究。
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Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria.线粒体中代谢关联机械活动的超微结构基础。I. 分离的肝线粒体中代谢稳态变化时的可逆超微结构改变。
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The reaction pathway of pig brain mitochondrial monoamine oxidase.猪脑线粒体单胺氧化酶的反应途径。
Eur J Biochem. 1968 Aug;5(3):316-20. doi: 10.1111/j.1432-1033.1968.tb00372.x.
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Evidence for the location of ferrochelatase on the inner membrane of rat liver mitochondria.大鼠肝脏线粒体内膜上铁螯合酶定位的证据。
Biochem Biophys Res Commun. 1968 Jun 28;31(6):977-82. doi: 10.1016/0006-291x(68)90549-4.
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Some observations upon a new inhibitor of monoamine oxidase in brain tissue.关于一种脑组织中单胺氧化酶新抑制剂的一些观察结果。
Biochem Pharmacol. 1968 Jul;17(7):1285-97. doi: 10.1016/0006-2952(68)90066-x.