Einer-Jensen N, Carter A M
Department of Physiology, Odense University, Denmark.
Med Hypotheses. 1995 Jun;44(6):471-4. doi: 10.1016/0306-9877(95)90508-1.
The adrenal cortex has a local stimulatory action on synthesis and secretion of adrenaline by the adrenal medulla. This interaction may be based on nervous transmission and/or on glucocorticoids secreted trom the cortex either exerting paracrine effects or reaching the medulla through the local vascular system. The existence of a dual capillary network, a portal system, now seems unlikely. However, a new concept is postulated: the high demand for glucocorticoids in the medulla may be met by local transfer to blood vessels within the adrenal gland, particularly the medullary arteries.
肾上腺皮质对肾上腺髓质肾上腺素的合成与分泌具有局部刺激作用。这种相互作用可能基于神经传递和/或皮质分泌的糖皮质激素，这些糖皮质激素要么发挥旁分泌作用，要么通过局部血管系统到达髓质。现在看来，双重毛细血管网络即门脉系统的存在不太可能。然而，一个新的概念被提出：髓质对糖皮质激素的高需求可能通过局部转移至肾上腺内的血管，尤其是髓质动脉来满足。
