Barut S
Department of Neurosurgery, Taksim Hospital, Istanbul, Turkey.
Neurosurg Rev. 1995;18(2):143-7. doi: 10.1007/BF00417673.
A surgically confirmed primary leptomeningeal malignant melanoma (PLMM) discovered at the parietal region is reported in a 72-year-old male. He developed progressive right hemiparesis and speech disorders caused by a parietal large mass that simulated a growing meningioma. A well-defined, dark-black tumor was removed completely and was histopathologically diagnosed as a malignant melanoma. No melanomas were detected by systemic clinical and radiological examination, including dermatological and ophthalmologic examinations. Follow-up examination 18 months postoperatively showed no evidence of recurrence of the tumor. The patient gradually became bedridden probably because of decreased general activity possibly due to brain atrophy and died of cardiac failure without any evidence of recurrence. Because of the absence of other systemic localizations, we consider this melanoma as primary. A favorable outcome was obtained by surgical treatment alone.
本文报道了一名72岁男性,其在顶叶区域发现了经手术确诊的原发性软脑膜恶性黑色素瘤(PLMM)。他因顶叶的一个巨大肿块出现进行性右半身轻瘫和言语障碍,该肿块疑似生长中的脑膜瘤。一个边界清晰的深黑色肿瘤被完全切除,组织病理学诊断为恶性黑色素瘤。包括皮肤科和眼科检查在内的全身临床和放射学检查均未发现黑色素瘤。术后18个月的随访检查未发现肿瘤复发迹象。患者可能由于脑萎缩导致全身活动减少,逐渐卧床不起,最终死于心力衰竭,未发现任何复发迹象。由于没有其他全身定位,我们认为该黑色素瘤为原发性。仅通过手术治疗就获得了良好的结果。