豚鼠中通过声音预处理对噪声性创伤的保护作用似乎不是由中耳肌肉介导的。

Protection against noise trauma by sound conditioning in the guinea pig appears not to be mediated by the middle ear muscles.

作者信息

Dagli S, Canlon B

机构信息

Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Neurosci Lett. 1995 Jul 14;194(1-2):57-60. doi: 10.1016/0304-3940(95)11726-d.

DOI:10.1016/0304-3940(95)11726-d

PMID:7478213

Abstract

The aim of this study was to test whether the middle ear muscles (MEM) play a significant role in the phenomenon of sound conditioning in guinea pigs. After inducing a temporary threshold shift by noise exposure (2767 Hz tone, 103 dB SPL, 5 min), the magnitude and duration of loss, as well as the rate of recovery of the amplitude of the distortion product emission was determined at 1.75, 2.2, 2.8, and 3.5 kHz followed for 90 min post-exposure for (1) a sound conditioned group with intact MEM, and (2) a sound conditioned group with paralyzed MEM. Significant differences were not found for any of the distortion product parameters tested. The results suggest that the MEM do not significantly contribute to protection against noise trauma by sound conditioning.

摘要

本研究的目的是测试中耳肌肉（MEM）在豚鼠声音调节现象中是否发挥重要作用。在通过噪声暴露（2767 Hz音调，103 dB SPL，5分钟）诱导暂时性阈移后，于暴露后90分钟内在1.75、2.2、2.8和3.5 kHz处测定损失的幅度和持续时间以及畸变产物发射幅度的恢复率，受试对象为（1）中耳肌肉完整的声音调节组，以及（2）中耳肌肉麻痹的声音调节组。在所测试的任何畸变产物参数中均未发现显著差异。结果表明，中耳肌肉对声音调节预防噪声性创伤没有显著作用。