Stack B C, Futran N D, Ridley M B, Schultz S, Sillman J S
Division of Otolaryngology-Head and Neck Surgery, University of South Florida College of Medicine, USA.
Otolaryngol Head Neck Surg. 1995 Nov;113(5):550-7. doi: 10.1177/019459989511300505.
Postoperative monitoring of microvascular free-tissue transfer is essential to the early identification and correction of vascular compromise. Laser Doppler flowmetry is a noninvasive monitor of capillary bed perfusion. Its current clinical use requires continuous monitoring and trend analysis to detect changes in capillary perfusion. This study investigated the hypothesis that signal averaging of laser Doppler flowmetry output triggered by a fixed point in the cardiac cycle would provide accurate information about the microvascular flow patterns not dependent on trend analysis. These results indicate that averaged waveform analysis allowed for a rapid, objective, and statistically significant distinction between a viable myocutaneous flap and one with vascular compromise in a porcine model. Moreover, this technique allows for distinction between venous and arterial insufficiency.
微血管游离组织移植术后监测对于早期识别和纠正血管受压至关重要。激光多普勒血流仪是一种监测毛细血管床灌注的非侵入性方法。其目前的临床应用需要连续监测和趋势分析以检测毛细血管灌注的变化。本研究探讨了这样一个假设，即由心动周期中的一个固定点触发的激光多普勒血流仪输出信号平均化将提供不依赖于趋势分析的有关微血管血流模式的准确信息。这些结果表明，在猪模型中，平均波形分析能够快速、客观且在统计学上显著地区分存活的肌皮瓣和存在血管受压的肌皮瓣。此外，该技术能够区分静脉性和动脉性供血不足。
