Jindal R M, Popescu I
Department of Surgery, Indiana University School of Medicine, Indianapolis 46202, USA.
Postgrad Med J. 1995 Sep;71(839):513-24. doi: 10.1136/pgmj.71.839.513.
It has been known for some time that a variety of liver diseases affect kidney function, but renal dysfunction associated with orthotopic liver transplantation has received scant attention. Although the mechanisms mediating these abnormalities are incompletely defined, advances in the understanding of renal pathophysiology after liver transplantation have made it possible to develop new treatment strategies. Aggressive and early intervention to diagnose and treat renal complications associated with liver transplantation should be the goal for transplant centres.
一段时间以来,人们已经知道多种肝脏疾病会影响肾功能,但原位肝移植相关的肾功能障碍却很少受到关注。尽管介导这些异常的机制尚未完全明确,但肝移植后肾脏病理生理学认识的进展使得制定新的治疗策略成为可能。积极并早期干预以诊断和治疗与肝移植相关的肾脏并发症应成为移植中心的目标。