Jindal R M, Tepper M A, Soltys K, Cho S I
Transplantation Services, University Hospital, Boston, MA.
Mt Sinai J Med. 1994 Jan;61(1):51-6.
DSG appears to have a unique, although as yet undefined, mechanism of action and may be a useful immunosuppressive agent. Because DSG is effective in reducing preformed antibodies in the xenograft situation, it may have a significant advantage in ABO-incompatible grafts in transplant recipients with high panel-reactive antibodies. Most important, DSG may have a definitive role in immunosuppressive therapy for pancreatic grafts.
