Mentzel T, Kriegsmann J, Kosmehl H, Katenkamp D
Institut für Pathologie, Friedrich-Schiller-Universität, Jena.
Pathologe. 1995 Sep;16(5):359-63. doi: 10.1007/s002920050115.
We report the case of an ectopic hamartomatous thymoma in a 56-year-old male patient. The lesion arose subcutaneously in the supraclavicular region. Histologically, the well-circumscribed but unencapsulated tumour was composed of uniform fusiform tumour cells. In addition, mature fatty tissue, scattered T-lymphocytes, and an epithelial and a myoepithelial tumour cell component were found. The epithelial differentiation of the spindle cell tumour component was confirmed immunohistochemically and by electron microscopy. Ectopic hamartomatous thymoma has to be distinguished from ectopic cervical thymoma, thymolipoma, ectopic salivary tissue, teratoma, peripheral nerve sheath tumours, malignant epithelial tumours with thymus-like differentiation, biphasic synovial sarcoma, and skin adnexal tumours.
我们报告了一例56岁男性患者的异位错构瘤性胸腺瘤病例。病变发生于锁骨上区域的皮下。组织学上,边界清楚但无包膜的肿瘤由形态一致的梭形肿瘤细胞组成。此外,还发现了成熟脂肪组织、散在的T淋巴细胞以及上皮和肌上皮肿瘤细胞成分。梭形细胞肿瘤成分的上皮分化通过免疫组织化学和电子显微镜得以证实。异位错构瘤性胸腺瘤必须与异位宫颈胸腺瘤、胸腺脂肪瘤、异位涎腺组织、畸胎瘤、周围神经鞘瘤、具有胸腺样分化的恶性上皮肿瘤、双相滑膜肉瘤以及皮肤附属器肿瘤相鉴别。