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英国高发病率地区的粟粒性肺结核:布莱克本,1978年至1993年

Miliary tuberculosis in a high prevalence area of the U.K.: Blackburn 1978-1993.

作者信息

Ormerod L P, Horsfield N

机构信息

Chest Clinic, Blackburn Royal Infirmary, UK.

出版信息

Respir Med. 1995 Sep;89(8):555-7. doi: 10.1016/0954-6111(95)90157-4.

Abstract

Thirty-nine cases of military tuberculosis treated between 1978-1993 in a district with a high incidence of tuberculosis are reported. Twenty-eight patients were of Indian Subcontinent (ISC) ethnic origin, 10 patients were Caucasian and one patient was Chinese. Mortality at 10% in both Caucasian (chi2 4.94; 0.05 > P > 0.01) and ISC patients (chi2 10.22; 0.001 > P) were significantly lower than in a recently reported series from Edinburgh, as was the proportion of post mortem diagnoses of miliary tuberculosis (chi2 6.35; 0.02 > P > 0.01). Both the rate of miliary tuberculosis and the average age at diagnosis in Caucasian patients were lower than in the Edinburgh series suggesting that miliary tuberculosis could be under-diagnosed in the elderly Caucasian population in the Blackburn district. The better outcome of those diagnosed in life may be partly due to heightened awareness of tuberculosis locally and partly due to treatment by a centralized tuberculosis service.

摘要

报告了1978年至1993年期间在一个结核病高发地区治疗的39例粟粒性结核病病例。28例患者为印度次大陆(ISC)族裔,10例患者为白种人,1例患者为华裔。白种人(χ² 4.94;0.05>P>0.01)和ISC患者(χ² 10.22;0.001>P)的死亡率均显著低于爱丁堡最近报告的系列研究,粟粒性结核病的尸检诊断比例也是如此(χ² 6.35;0.02>P>0.01)。白种人患者的粟粒性结核病发病率和诊断时的平均年龄均低于爱丁堡系列研究,这表明在布莱克本地区的老年白种人群中,粟粒性结核病可能未得到充分诊断。那些在生前被诊断出的患者预后较好,部分原因可能是当地对结核病的认识提高,部分原因可能是由集中的结核病服务机构进行治疗。

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