Lukash N V, Polishchuk T F
Lik Sprava. 1995 Jan-Feb(1-2):53-5.
A peptide was obtained at our chair, from the mucous membrane of the stomach of the pig, using a method of acid extraction. The above peptide belongs to the group of cytomedines and is conventionally called "mucozaline". As many as 80 Wistar male rats were used in comparative evaluation of thymaline, dallargine and "mucozaline" for their effect on the course of duodenal ulcer in the rat. The results obtained showed that regulatory peptides play an important part in protection of the gastric and duodenal mucosa against the damaging factors. Of the above agents, it is "mucozaline" that has the greatest protective action, with dallargine and thymaline following it in the declining order.
在我们教研室，通过酸提取法从猪胃黏膜中获得了一种肽。上述肽属于细胞调节因子类，通常被称为“黏液碱”。在对胸腺素、达勒金和“黏液碱”对大鼠十二指肠溃疡病程的影响进行比较评估时，使用了多达80只雄性Wistar大鼠。所获得的结果表明，调节肽在保护胃和十二指肠黏膜免受损伤因素的影响方面起着重要作用。在上述药物中，“黏液碱”具有最大的保护作用，达勒金和胸腺素依次递减。
