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帕罗西汀对电休克治疗期间癫痫发作时长的影响。

Effect of paroxetine on seizure length during electroconvulsive therapy.

作者信息

Curran S

机构信息

Department of Psychiatry, University of Leeds, United Kingdom.

出版信息

Acta Psychiatr Scand. 1995 Sep;92(3):239-40. doi: 10.1111/j.1600-0447.1995.tb09576.x.

DOI:10.1111/j.1600-0447.1995.tb09576.x
PMID:7484206
Abstract

This study reports the effect of paroxetine, a selective serotonin reuptake inhibitor, on seizure length during electroconvulsive therapy. Seven inpatients taking paroxetine were compared with 7 controls taking tricyclic antidepressants. The mean seizure length of the paroxetine group was approximately twice that of the control group.

摘要

本研究报告了选择性5-羟色胺再摄取抑制剂帕罗西汀对电休克治疗期间癫痫发作时长的影响。将7名服用帕罗西汀的住院患者与7名服用三环类抗抑郁药的对照者进行了比较。帕罗西汀组的平均癫痫发作时长约为对照组的两倍。

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Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel.抗抑郁药物帕罗西汀可阻断Kv3.1钾通道的开放孔道。
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Selecting an antidepressant for use in a patient with epilepsy. Safety considerations.为癫痫患者选择抗抑郁药。安全性考量。
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